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Multiple Choice

Which electrolyte imbalance commonly accompanies metabolic acidosis?

Metabolic acidosis causes hydrogen ions to accumulate in the extracellular fluid. To maintain electroneutrality, H+ moves into cells while potassium ions move out into the extracellular space, raising serum potassium. Coupled with reduced renal potassium excretion during acidosis, this leads to hyperkalemia. This pattern is the classic electrolyte change seen with metabolic acidosis and is clinically important because elevated potassium can affect cardiac function and must be addressed during treatment. Hyponatremia, hypokalemia, or hypercalcemia do not typically accompany metabolic acidosis in the same characteristic way.

Metabolic acidosis causes hydrogen ions to accumulate in the extracellular fluid. To maintain electroneutrality, H+ moves into cells while potassium ions move out into the extracellular space, raising serum potassium. Coupled with reduced renal potassium excretion during acidosis, this leads to hyperkalemia. This pattern is the classic electrolyte change seen with metabolic acidosis and is clinically important because elevated potassium can affect cardiac function and must be addressed during treatment. Hyponatremia, hypokalemia, or hypercalcemia do not typically accompany metabolic acidosis in the same characteristic way.